Altered Fat Tissue Distribution in Young Adult Men Who Had Low Birth Weight
نویسندگان
چکیده
منابع مشابه
Altered fat tissue distribution in young adult men who had low birth weight.
Numerous studies have implicated impaired early growth (low birth weight [LBW]) as a risk factor for the development of obesity (1) and type 2 diabetes (2). Obesity, particularly abdominal obesity, is associated with an increased risk of insulin resistance and type 2 diabetes, and although the mechanistic basis is not fully known, several characteristics of the metabolically active visceral fat...
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BACKGROUND Low birth weight (LBW) is associated with increased future risk of insulin resistance and type 2 diabetes mellitus. The underlying molecular mechanisms remain poorly understood. We have previously shown that young LBW men have reduced skeletal muscle expression of PI3K p85alpha regulatory subunit and p110beta catalytic subunit, PKCzeta and GLUT4 in the fasting state. The aim of this ...
متن کاملEarly differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.
Several studies have linked low birth weight (LBW) and type 2 diabetes. We investigated hepatic and peripheral insulin action including intracellular glucose metabolism in 40 19-year-old men (20 LBW, 20 matched control subjects), using the hyperinsulinemic-euglycemic clamp technique at two physiological insulin levels (10 and 40 mU/m(2) per min), indirect calorimetry, and [3-(3)H]glucose. Insul...
متن کاملYoung adult outcomes of very-low-birth-weight children.
Information on the young adult outcomes of the initial survivors of neonatal intensive care has been reported from the United States, Canada, Australia, Great Britain and other European countries. The studies have varied with regard to whether they were regional or hospital-based, their birth-weight group and gestational age, rates of survival, socio-demographic background, and measures of asse...
متن کاملlow birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
background: women engaged with polycystic ovarian syndrome (pcos), as the commonest endocrine disorder, are known to have a specific type of adiposity. birth weight is among different contributors reported to be responsible for this diversity. objective: we aimed to compare the relation between birth weight and body fat mass (bfm)/ body lean mass (blm) in pcos and their age and body mass index ...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2004
ISSN: 0149-5992,1935-5548
DOI: 10.2337/diacare.28.1.151